Corrigendum: Masculinised Behaviour of XY Females in a Mammal with Naturally Occurring Sex Reversal
نویسندگان
چکیده
“We are grateful to J. Britton-Davidian, T. J. Robinson, and J. Watson for their contributions in collecting the founder animals, J. Perez and M. Perriat-Sanguinet for their help in maintaining the breeding colony, P.-A. Crochet for advice on statistical analyses and C.M.-S. Dufour and Y. Latour for helpful discussions. This work was supported by the French National Research Agency (ANR grant “SEXYMUS”, No. 10-JCJC-1605), and the Del Duca Foundation (Institut de France, “Subvention scientifique” grant). This is a publication ISEM no. 2016-45.”
منابع مشابه
Masculinised Behaviour of XY Females in a Mammal with Naturally Occuring Sex Reversal
Most sex differences in phenotype are controlled by gonadal hormones, but recent work on laboratory strain mice that present discordant chromosomal and gonadal sex showed that sex chromosome complement can have a direct influence on the establishment of sex-specific behaviours, independently from gonads. In this study, we analyse the behaviour of a rodent with naturally occurring sex reversal: ...
متن کاملI-17: The Mechanism of Gonadal Sex Determination
Background In mammals, a single exon gene SRY on the Y-chromosome is activated in the XY gonadal primordium and initiates a cascade of molecular and morphological events leading to testicular differentiation. SRY-encoded protein (SRY) is a transcription factor harboring a HMG-box DNAbinding motif that upregulates SOX9, which encodes another transcription factor sharing the DNA binding motif wit...
متن کاملI-18: The Role of Sex Chromosomes in Female Germ Cell Differentiation
Background When gonadal sex reversal occurs in mammalian species, the resultant XX males and XY females become infertile or subfertile, suggesting critical roles of sex chromosomes in germ cell differentiation. The objective of our study is to clarify the mechanism of infertility in the B6.YTIR (XY) sex-reversed female mouse, which can be attributed to a failure in the second meiotic division i...
متن کاملThe dominant white spotting oncogene allele Kit(W-42J) exacerbates XY(DOM) sex reversal.
The Y chromosome from certain populations of M. m. domesticus is incapable of normal testis determination in the B6 inbred strain resulting in XY hermaphrodites or XY females (XY(DOM) sex reversal). B6 consomic strains have been developed with either transient (B6-Y(AKR)) or severe (B6-Y(TIR)) XY(DOM) sex reversal. We report that a point mutation, the dominant white spotting oncogene allele, Ki...
متن کاملPermanent and functional male-to-female sex reversal in d-rR strain medaka (Oryzias latipes) following egg microinjection of o,p'-DDT.
Complete sex reversal of fish is accomplished routinely in aquaculture practices by exposing fish to exogenous sex steroids during gonadal differentiation. A variety of environmental chemicals are also active at sex steroid receptors and theoretically possess the potential to alter normal sexual differentiation in fish. However, in controlled environmental chemical exposures to date, only parti...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 6 شماره
صفحات -
تاریخ انتشار 2016